Y. C. Fung's Biodynamics: Circulation PDF

By Y. C. Fung

ISBN-10: 1475738846

ISBN-13: 9781475738841

ISBN-10: 1475738862

ISBN-13: 9781475738865

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Extra resources for Biodynamics: Circulation

Sample text

How the pump works is the subject of this chapter. In each cycle the left and right ventricles are first filled with blood from the left and right atria, respectively, in the diastolic phase of the cycle. Then by the deceleration of the blood stream a pressure field is generated, which closes the valves between the atria and the ventricles . The contraction of the heart muscle begins and the pressures in the ventricles rise. When the pressure in the left ventricle exceeds that in the aorta, and the pressure in the right ventricle exceeds that in the pulmonary artery, the aortic valve in the left and the pulmonary valve in the right are pushed open, and blood is ejected into the aorta and the lung.

Phase 2 represents isovolumic pressure development. Phase 3 represent s ejection of blood into the aorta. Phase 4 represents the isovolumic relaxation period . the four phases of the cardiac cycle. The area within the loop describes the external work (stroke work) done by the left ventricle as it contracts. The lower curve of the loop, phase I, (the arc AB in Fig. 4: 4), represents the ventricular filling. During this period the heart is in dia stole and the muscle is resting . The curve AB, therefore, should be the same as the pressure-volume (P- V) curve of a resting heart.

I) The solution of this differential equation is r' . (RK ), (2) where Po is the value of p at time t = O. This gives the pressure in the aorta as a function of the left ventricle ejection history Q (t ). Equation (2) work s remarkably well in correlating experimental data on the total blood flow Q with the blood pressure p, particularly during diastole. (See McDonald 1974, pp. ) Hence , in spite of the severity of the underlying assumptions it is quite useful. Turning now to the question of stress in the heart itself, there is another very simple anal ysis that is quite good.

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Biodynamics: Circulation by Y. C. Fung


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