Biothiols by Packer L. PDF

By Packer L.

This specific, cutting-edge reference provides a close account of the molecular mechanisms underlying the a number of features of biothiols-emphasizing the organic and medical implications of interactions among oxidants and biothiols.

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Pryor, H. Ischiropoulos, and J. S. Beckman, Chem. Res. Toxicol. 5, 834 (1992). 28 j. j. Moreno and W. A. Pryor, Chem. Res. Toxicol. 5, 425 (1992). 29 R. Radi, J. S. Beckman, K. M. Bush, and B. A. Freeman, Arch. Biochem. Biophys. 288, 481 (1991). 30 R. Radi, J. S. Beckman, K. M. Bush, and B. A. Freeman, J. Biol. Chem. 266, 4244 (1991). 5 M N a O H . 32In contrast, the synthesis by mixing of the reactants in conventional glassware afforded yields between 45 and 50%. 31 Residual hydrogen peroxide can be removed by passage of the peroxynitrite solution through an MnO2 column, although it has been pointed out that this process may lead to the contamination of the solution by metals.

Free Radicals Biol. Med. 2, 261 (1986). 8 D. Ross, E. Albano, U. Nilsson, and P. Mold6us, Biochem. Biophys. Res. Commun. 125, 109 (1984). 9 D. Ross, R. Larsson, K. Norbeck, and P. Mold6us, Life Chem. Rep. 3, 112 (1985). 10 D. Ross, K. Norbeck, and P. Mold6us, J. Biol. Chem. 260, 15028 (1985). 11 p. j. O'Brien, Free Radical Biol. Med. 4, 169 (1988). 12 L. G. Forni, J. M6nig, V. O. Mora-Arellano, and R. L. Willson, J. Chem. , Perkin Trans. 2, 961 (1983). 13 O. Ito and M. Matsuda, in "Chemical Kinetics of Small Organic Radicals.

Asmus, this series, Vol. 186, p. 168. 16 B. C. Gilbert, in "Sulfur-Centered Reactive Intermediates in Chemistry and Biology" (C. -D. ), p. 135. Plenum, New York, 1990. 17 D. A. Armstrong, in "Sulfur-Centered Reactive Intermediates in Chemistry and Biology" (C. -D. ), p. 121. Plenum, New York, 1990. is D. A. Armstrong, in "Sulfur-Centered Reactive Intermediates in Chemistry and Biology" (C. -D. ), p. 341. Plenum, New York, 1990. 19 C. von Sonntag, in "Sulfur-Centered Reactive Intermediates in Chemistry and Biology" (C.

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Biothiols by Packer L.

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